ASCL1-mediated direct reprogramming: converting ventral midbrain astrocytes into dopaminergic neurons for Parkinson’s disease therapy

Author:

Yong Sang Hui1ORCID,Kim Sang-Mi23ORCID,Kong Gyeong Woon1ORCID,Ko Seung Hwan1ORCID,Lee Eun-Hye45ORCID,Oh Yohan12678ORCID,Park Chang-Hwan12ORCID

Affiliation:

1. Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea

2. Hanyang Biomedical Research Institute, Hanyang University, Seoul 04763, Korea

3. Center for Embryo and Stem Cell Research, CHA Advanced Research Institute, CHA University, Seongnam 13488, Korea

4. Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA

5. Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA

6. Department of Biochemistry and Molecular Biology, College of Medicine, Hanyang University, Seoul 04763, Korea

7. Hanyang Institute of Bioscience and Biotechnology, Hanyang University, Seoul 04763, Korea

8. Hanyang Institute of Advanced BioConvergence, Hanyang University, Seoul 04763, Korea

Funder

National Research Foundation of Korea

Ministry of Science and ICT, South Korea

Korea Dementia Research Center

Ministry of Health and Welfare

Publisher

Korean Society for Biochemistry and Molecular Biology - BMB Reports

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