Loss of hepatic Sirt7 accelerates diethylnitrosamine (DEN)-induced formation of hepatocellular carcinoma by impairing DNA damage repair

Author:

Kim Yuna1,Kang Baeki E.2,Gariani Karim3,Gariani Joanna4,Lee Junguee5,Kim Hyun-Jin2,Lee Chang-Woo1,Schoonjans Kristina6,Auwerx Johan6,Ryu Dongryeol17ORCID

Affiliation:

1. Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 16419, Korea

2. Department of Physiology, Sungkyunkwan University School of Medicine, Suwon 16419, Korea

3. Service of Endocrinology, Diabetes, Nutrition and Therapeutic Patient Education, Geneva University Hospitals, Geneva 1205, Switzerland

4. Department of Radiology, Hirslanden Grangettes Clinic, Geneva 1224, Switzerland

5. Department of Pathology, Konyang University, Daejeon 35365, Korea

6. Institute of Bioengineering, Ecole Polytechnique Federale de Lausanne, Lausanne 1015, Switzerland

7. Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju 61005, Korea

Funder

National Research Foundation of Korea

Ministry of Science and ICT, South Korea

Gwangju Institute of Science and Technology

Publisher

Korean Society for Biochemistry and Molecular Biology - BMB Reports

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