Role of the Androgen-Androgen Receptor Axis in the Treatment Resistance of Advanced Prostate Cancer: From Androgen-Dependent to Castration Resistant and Further

Author:

FUJIMOTO Naohiro1

Affiliation:

1. Department of Urology, School of Medicine, University of Occupational and Environmental Health, Japan

Publisher

The University of Occupational and Environmental Health, Japan

Subject

Public Health, Environmental and Occupational Health,General Medicine

Reference63 articles.

1. 1. National Cancer Center (2015): Projected cancer incidence in 2015, Projected Cancer Statistics, 2015, Tokyo http://ganjoho.jp/en/public/statistics/short_pred.html, [Feb 15 2016]

2. 2. Huggins C & Hodges CV (1941): Studies on prostatic cancer. I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res 1: 293-297

3. 3. Chung PH, Gayed BA, Thoreson GR & Raj GV (2013): Emerging drugs for prostate cancer. Expert Opin Emerg Drugs 18: 533-550

4. 4. Labrie F (2011): Blockade of testicular and adrenal androgens in prostate cancer treatment. Nat Rev Urol 8: 73-85

5. 5. Montgomery RB, Mostaghel EA, Vessella R, Hess DL, Kalhorn TF, Higano CS, True LD & Nelson PS (2008): Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res 68: 4447-4454

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