Author:
Mazza Marianna,Margoni Stella,Mandracchia Giuseppe,Donofrio Guglielmo,Fischetti Alessia,Kotzalidis Georgios D,Marano Giuseppe,Simonetti Alessio,Janiri Delfina,Moccia Lorenzo,Marcelli Ilaria,Sfratta Greta,Berardis Domenico De,Ferrara Ottavia,Bernardi Evelina,Restaino Antonio,Lisci Francesco Maria,D'Onofrio Antonio Maria,Brisi Caterina,Grisoni Flavia,Calderoni Claudia,Ciliberto Michele,Brugnami Andrea,Rossi Sara,Spera Maria Chiara,Masi Valeria De,Marzo Ester Maria,Abate Francesca,Boggio Gianluca,Anesini Maria Benedetta,Falsini Cecilia,Quintano Anna,Torresi Alberto,Militenda Miriam,Bartolucci Giovanni,Biscosi Marco,Ruggiero Sara,Giudice Luca Lo,Mastroeni Giulia,Benini Elisabetta,Benedetto Luca Di,Caso Romina,Pesaresi Francesco,Traccis Francesco,Onori Luca,Chisari Luca,Monacelli Leonardo,Acanfora Mariateresa,Gaetani Eleonora,Marturano Monia,Barbonetti Sara,Specogna Elettra,Bardi Francesca,Chiara Emanuela De,Stella Gianmarco,Zanzarri Andrea,Tavoletta Flavio,Crupi Arianna,Battisti Giulia,Monti Laura,Camardese Giovanni,Chieffo Daniela,Gasbarrini Antonio,Scambia Giovanni,Sani Gabriele
Abstract
BACKGROUND
Interstitial cystitis/bladder pain syndrome (IC/BPS) is an at least 6-mo noninfectious bladder inflammation of unknown origin characterized by chronic suprapubic, abdominal, and/or pelvic pain. Although the term cystitis suggests an inflammatory or infectious origin, no definite cause has been identified. It occurs in both sexes, but women are twice as much affected.
AIM
To systematically review evidence of psychiatric/psychological changes in persons with IC/BPS.
METHODS
Hypothesizing that particular psychological characteristics could underpin IC/BPS, we investigated in three databases the presence of psychiatric symptoms and/or disorders and/or psychological characteristics in patients with IC/BPS using the following strategy: ("interstitial cystitis" OR "bladder pain syndrome") AND ("mood disorder" OR depressive OR antidepressant OR depression OR depressed OR hyperthymic OR mania OR manic OR rapid cyclasterisk OR dysthymiasterisk OR dysphoriasterisk).
RESULTS
On September 27, 2023, the PubMed search produced 223 articles, CINAHL 62, and the combined PsycLIT/PsycARTICLES/PsycINFO/Psychology and Behavioral Sciences Collection search 36. Search on ClinicalTrials.gov produced 14 studies, of which none had available data. Eligible were peer-reviewed articles reporting psychiatric/psychological symptoms in patients with IC/BPS, i.e. 63 articles spanning from 2000 to October 2023. These studies identified depression and anxiety problems in the IC/BPS population, along with sleep problems and the tendency to catastrophizing.
CONCLUSION
Psychotherapies targeting catastrophizing and life stress emotional awareness and expression reduced perceived pain in women with IC/BPS. Such concepts should be considered when implementing treatments aimed at reducing IC/BPS-related pain.
Publisher
Baishideng Publishing Group Inc.