Wastewater-based SARS-CoV-2 airport surveillance: key trends at the Cape Town International Airport-Reference-Cited by-同舟云学术

Wastewater-based SARS-CoV-2 airport surveillance: key trends at the Cape Town International Airport

Published:2023-02-28 Issue:3 Volume:21 Page:402-408
ISSN:1477-8920
Container-title:Journal of Water and Health
language:en
Short-container-title:

Author:

Nkambule Sizwe¹^ORCID,Johnson Rabia²³,Mathee Angela¹⁴⁵,Mahlangeni Nomfundo¹,Webster Candice¹,Horn Suranie¹⁶,Mangwana Noluxabiso²⁷,Dias Stephanie²,Sharma Jyoti Rajan²,Ramharack Pritika²⁸,Louw Johan²⁹,Reddy Tarylee¹⁰,Surujlal-Naicker Swastika¹¹,Mdhluli Mongezi¹²,Gray Glenda¹³,Muller Christo²³⁹,Street Renee¹⁴

Affiliation:

1. a Environment & Health Research Unit, South African Medical Research Council (SAMRC), Durban 4091, South Africa

2. b Biomedical Research and Innovation Platform (BRIP), South African Medical Research Council (SAMRC), Tygerberg 7505, South Africa

3. c Centre for Cardio-Metabolic Research in Africa, Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Stellenbosch 7600, South Africa

4. d Environmental Health Department, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa

5. e School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

6. m Occupational Hygiene and Health Research Initiative, North-West University, Potchefstroom, South Africa

7. f Department of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa

8. g Discipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban 4001, South Africa

9. h Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa

10. i Biostatistics Unit, South African Medical Research Council (SAMRC), Durban 4091, South Africa

11. j Scientific Services, Water and Sanitation Department, City of Cape Town Metropolitan Municipality, Cape Town 8000, South Africa

12. k Chief Research Operations Office, South African Medical Research Council, Tygerberg 7050, South Africa

13. l Office of the President, South African Medical Research Council, Tygerberg 7050, South Africa

Abstract

Abstract Monitoring of SARS-CoV-2 RNA in wastewater has revealed the role of mobility in the transmission of coronavirus disease (COVID-19), and the surveillance of airport wastewater in cities across the world has demonstrated how travel entry points can give an indication of trends in transmission. This study undertook wastewater surveillance at the Cape Town International Airport (CTIA) to assess the use of a WBE approach to provide supplementary information on the presence of COVID-19 at a key air travel entry point in South Africa. Grab wastewater samples (n = 55) were collected from the CTIA wastewater pump station and analysed using quantitative real-time polymerase chain reaction (qRT-PCR) method. The study found a correlation between the wastewater data and clinical cases reported in the City of Cape Town during various time periods and during the peak of a COVID-19 wave. Highly elevated viral loads in the wastewater were observed at times there was increased mobility through the airport. The study also revealed elevated viral load levels at the airport despite the stricter restrictions and through the lower restrictions. The study findings indicate wastewater surveillance and airports can provide supplementary information to airport authorities to assess the impacts of imposed travel restrictions.

Funder

South African Medical Research Council

National Research Foundation

The Solidarity Fund

Publisher

IWA Publishing

Subject

Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,Waste Management and Disposal,Water Science and Technology

Link

https://iwaponline.com/jwh/article-pdf/21/3/402/1241358/jwh0210402.pdf

Reference11 articles.

1. Detection of SARS-CoV-2 RNA in commercial passenger aircraft and cruise ship wastewater: a surveillance tool for assessing the presence of COVID-19 infected travellers;Journal of Travel Medicine,2020

2. Detection of the Omicron (B. 1.1. 529) variant of SARS-CoV-2 in aircraft wastewater;Science of the Total Environment,2022

3. First confirmed detection of SARS-COV-2 in untreated municipal and aircraft wastewater in Dubai, UAE: the use of wastewater based epidemiology as an early warning tool to monitor the prevalence of COVID-19;Science of the Total Environment,2021

4. CDC 2020 2019-Novel Coronavirus (2019-nCoV) Real-Time RT-PCR Panel Primers and Probes. Available from: https://www.cdc.gov/coronavirus/2019-ncov/downloads/rt-pcr-panel-primer-probes.pdf (accessed 6 October 2021).

5. SARS-CoV-2 from faeces to wastewater treatment: what do we know? A review;Science of the Total Environment,2020

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Long-term wastewater monitoring of SARS-CoV-2 viral loads and variants at the major international passenger hub Amsterdam Schiphol Airport: A valuable addition to COVID-19 surveillance;Science of The Total Environment;2024-08

2. Systematic SARS-CoV-2 S-gene sequencing in wastewater samples enables early lineage detection and uncovers rare mutations in Portugal;Science of The Total Environment;2024-04

3. Systematic SARS-CoV-2 S Gene Sequencing in Wastewater Samples Enables Early Lineage Detection and Uncovers Rare Mutations in Portugal;2023-10-31

4. The lavatory lens: Tracking the global movement of pathogens via aircraft wastewater;Critical Reviews in Environmental Science and Technology;2023-08-10