Affiliation:
1. Anna University, Chennai 600 025, India
2. Purdue University, West Lafayette, IN 47907, USA
Abstract
An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper deals with the electric field distribution study of a tissue model using MAXWELL 3D Simulator. Our results indicate that tumor tissue had lower electric field strength compared to normal cells, which makes them susceptible to electrical-pulse-mediated drug delivery. This difference could be due to the altered properties of tumor cells compared to normal cells, and our results corroborate this.
Subject
Cancer Research,Pharmacology (medical),Oncology
Cited by
11 articles.
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