Affiliation:
1. Yaroslavl State Medical University
2. I.M. Sechenov First Moscow State Medical University (Sechenov University); Lomonosov Moscow State University
3. I.M. Sechenov First Moscow State Medical University (Sechenov University)
4. Moscow Center for Health Problems under the Government of Moscow
Abstract
The aim of the review. To analyze the prevalence of sarcopenic obesity among elderly and senile people, to assess its causes, and to present modern methods for its prevention and physical rehabilitation.This review article discusses the most recent evidence on age-related changes in fat and muscle tissue, and on calorie restriction and exercise that have positive effect on physical performance in older people with sarcopenic obesity. In addition, potential gaps in clinical practice guidelines that merit attention in future research are identified and analyzed.Search strategy. We used the following key words to define participation in the review:“sarcopenic obesity”, “sarcopenia with obesity”, “sarcopenia”, “elderly/old age”. Inclusion and exclusion criteria. The review included original research results (reviews, meta-analyses). Editorials, proceeding of the conferences, and research protocols were excluded. The study sample included women and men of any race aged ≥ 60 years with a diagnosis of sarcopenic obesity and with preserved locomotion function. Articles involving hospital patients were also excluded. Non-human studies and studies that did not report precise intervention criteria (e. g., nutrition, exercise, duration, etc.) were excluded.The literature search was conducted in four electronic databases: PubMed, Cochrane Library, Springer, Scopus, for the period from 2013 to August 1, 2023. There were no restrictions on the language of the publication.
Reference64 articles.
1. Nations U. World population prospects: The 2017 revisions, key findings and advance tables. Working Paper No ESA/P/WP/248. 2017. URL: https://desapublications.un.org/publications/worldpopulation-prospects-2017-revision [date of access: 01.09.2023].
2. Batsis JA, Villareal DT. Sarcopenic obesity in older adults: An etiology, epidemiology and treatment strategies. Nat Rev Endocrinol. 2018; 14(9): 513-537. doi: 10.1038/s41574-018-0062-9
3. Bray GA, Kim KK, Wilding JPH, World Obesity Federation. Obesity: A chronic relapsing progressive disease process. A position statement of the World Obesity Federation. Obes Rev. 2017; 18(7): 715-723. doi: 10.1111/obr.12551
4. Bluher M. Obesity: Global epidemiology and pathogenesis. Nat Rev Endocrinol. 2019; 15(5): 288-298. doi: 10.1038/s41574-019-0176-8
5. Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, et al. Sarcopenia: An undiagnosed condition in older adults. Current consensus definition: Prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc. 2011; 12(4): 249-256. doi: 10.1016/j.jamda.2011.01.003