The diagnostic value of calcium binding protein S100A8/A9 and S100A12 in acute pancreatitis-Reference-Cited by-同舟云学术

The diagnostic value of calcium binding protein S100A8/A9 and S100A12 in acute pancreatitis

Published:2022-05-30 Issue:3 Volume:5 Page:844-849
ISSN:2636-8579
Container-title:Journal of Health Sciences and Medicine
language:en
Short-container-title:J Health Sci Med / JHSM

Author:

BARDAKCI Okan¹,DAŞ Murat¹,ŞEHİTOĞLU Hilal¹,ÜNAL ÇETİN Ece¹,ATALAY Ünzile¹,KÜÇÜK Uğur¹,KAMIŞ Fatih¹,TANOĞLU Alpaslan²,BEYAZIT Yavuz¹

Affiliation:

1. CANAKKALE ONSEKIZ MART UNIVERSITY, ÇANAKKALE HEALTH ACADEMY

2. SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL SANCAKTEPE ŞEHİR PROF. DR. İLHAN VARANK SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI

Abstract

Background: S100A8/A9 and S100A12 which are the major calcium-binding proinflammatory proteins secreted by granulocytes, has been proposed to be related to distinct disease states of inflammatory origin. This study aims to explore the circulating levels of S100A8/A9 and S100A12 in acute pancreatitis (AP) and reveal their relationship with conventional inflammatory markers. Material and Method: Serum S100A8/A9 and S100A12 were determined in AP patients (male/female: 17/13) by using a specific enzyme-linked immunosorbent assay (ELISA) method at both onset and remission and in 30 healthy controls (male/female: 17/13). Results: Significantly higher S100A8/A9 and S100A12 levels were found in AP patients compared to healthy controls (p

Publisher

Journal of Health Sciences and Medicine

Subject

General Medicine

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