Retrospective screening of solid organ donors in Italy, 2009, reveals unpredicted circulation of West Nile virus

Author:

Capobianchi M R12,Sambri V31,Castilletti C2,Pierro A M3,Rossini G3,Gaibani P3,Cavrini F3,Selleri M2,Meschi S2,Lapa D2,Di Caro A2,Grossi P4,De Cillia C5,Venettoni S5,Landini M P3,Ippolito G2,Nanni Costa A5,on behalf of the Italian Transplant Network Collective6

Affiliation:

1. These authors contributed equally to the work and share first authorship

2. National Institute for Infectious Diseases (INMI) “L. Spallanzani”, Rome, Italy

3. Regional Reference Centre for Microbiological Emergencies (CRREM), Unit of Clinical Microbiology, St Orsola University Hospital, University of Bologna, Bologna, Italy

4. Department of Infectious Diseases, University of Insubria, Varese, Italy

5. National Transplant Centre, Rome, Italy

6. Members are listed at the end of the article

Abstract

Since the occurrence of West Nile virus (WNV) infection in humans in 2008 in Italy, concerns have been raised about the potential risks associated with solid organ transplantation (SOT). A nationwide retrospective survey showed that 1.2% of SOT donors in 2009 were WNV-seropositive and demonstrated that human WNV infection is distributed throughout several Italian regions. Transmission of WNV or other arboviruses through SOT is a possibility and risk assessment should be carried out before SOT to avoid infection through transplantation.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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