Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom: mid-season analysis 2010/11-Reference-Cited by-同舟云学术

Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom: mid-season analysis 2010/11

Published:2011-02-10 Issue:6 Volume:16 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Pebody R¹,Hardelid P¹,Fleming D M²,McMenamin J³,Andrews N¹,Robertson C⁴³,Thomas D R⁵,Sebastianpillai P⁶,Ellis J⁶,Carman W⁷,Wreghitt T⁸,Zambon M⁶,Watson J M¹

Affiliation:

1. Health Protection Agency Health Protection Services – Colindale, London, United Kingdom

2. Royal College of General Practitioners Research and Surveillance Centre, Birmingham, United Kingdom

3. Health Protection Scotland, Glasgow, United Kingdom

4. University of Strathclyde, Glasgow, United Kingdom

5. Public Health Wales, Cardiff, United Kingdom

6. Health Protection Agency Microbiology Services – Colindale, London, United Kingdom

7. West of Scotland Specialist Virology Centre, Glasgow, United Kingdom

8. Health Protection Agency Microbiology Services, Cambridge, United Kingdom

Abstract

This study provides mid-season estimates of the effectiveness of 2010/11 trivalent influenza vaccine and previous vaccination with monovalent influenza A(H1N1)2009 vaccine in preventing confirmed influenza A(H1N1)2009 infection in the United Kingdom in the 2010/11 season. The adjusted vaccine effectiveness was 34% (95% CI: -10 - 60%) if vaccinated only with monovalent vaccine in the 2009/10 season; 46% (95% CI: 7 - 69%) if vaccinated only with trivalent influenza vaccine in the 2010/11 season and 63% (95% CI: 37 - 78%) if vaccinated in both seasons.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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