First human case of Usutu virus neuroinvasive infection, Italy, August-September 2009-Reference-Cited by-同舟云学术

First human case of Usutu virus neuroinvasive infection, Italy, August-September 2009

Published:2009-12-17 Issue:50 Volume:14 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Pecorari M¹,Longo G²,Gennari W¹,Grottola A¹,Sabbatini A MT¹,Tagliazucchi S¹,Savini G³,Monaco F³,Simone M L⁴,Lelli R³,Rumpianesi F¹

Affiliation:

1. Department of Diagnostic and Laboratory Services and Legal Medicine, University of Modena and Reggio Emilia, Azienda Ospedaliera Policlinico, Modena, Italy

2. Department of Oncology and Hematology, University of Modena and Reggio Emilia, Azienda Ospedaliera Policlinico, Modena, Italy

3. Department. of Virology, National Reference Centre for West Nile and Usutu disease, OIE Reference Laboratory for Bluetongue, Istituto Zooprofilattico Sperimentale dell’Abruzzo e Molise ‘G. Caporale’, Teramo, Italy

4. Department of Biomedical Sciences, University of Modena and Reggio Emilia, Modena, Italy

Abstract

We report the first worldwide case of Usutu virus (USUV) neuroinvasive infection in a patient with diffuse large B cell lymphoma who presented with fever and neurological symptoms and was diagnosed with meningoencephalitits. The cerebrospinal fluid was positive for USUV, and USUV was also demonstrated in serum and plasma samples by RT-PCR and sequencing. Partial sequences of the premembrane and NS5 regions of the viral genome were similar to the USUV Vienna and Budapest isolates.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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