Evaluation of immunochromatography tests for detection of novel GII.17 norovirus in stool samples

Author:

Khamrin P123,Thongprachum A32,Takanashi S23,Okitsu S32,Maneekarn N1,Hayakawa S2,Ushijima H23

Affiliation:

1. Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

2. Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan

3. Department of Developmental Medical Sciences, School of International Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Abstract

A novel GII.17 norovirus has emerged as a major cause of epidemic and endemic acute gastroenteritis in several countries in Asia. We used a small panel of stool samples in which GII.17 virus had been quantified by real-time RT-PCR to evaluate four commercially available norovirus immunochromatography (IC) kits. At least 108 copies/mL of GII.17 virus were required by each IC kit for a positive result, which is 1,000-fold more than that reported for these assays for GII.4 viruses.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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