Emergence of influenza A(H1N1)pdm09 genogroup 6B and drug resistant virus, India, January to May 2015-Reference-Cited by-同舟云学术

Emergence of influenza A(H1N1)pdm09 genogroup 6B and drug resistant virus, India, January to May 2015

Published:2016-02-04 Issue:5 Volume:21 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Parida Manmohan¹,Dash Paban Kumar¹,Kumar Jyoti S¹,Joshi Gaurav¹,Tandel Kundan¹,Sharma Shashi¹,Srivastava Ambuj¹,Agarwal Ankita¹,Saha Amrita¹,Saraswat Shweta¹,Karothia Divyanshi¹,Malviya Vatsala¹

Affiliation:

1. Division of Virology, Defence Research & Development Establishment (DRDE), Gwalior, India

Abstract

To investigate the aetiology of the 2015 A(H1N1)pdm09 influenza outbreak in India, 1,083 nasopharyngeal swabs from suspect patients were screened for influenza A(H1N1)pdm09 in the state of Madhya Pradesh. Of 412 positive specimens, six were further characterised by phylogenetic analysis of haemagglutinin (HA) sequences revealing that they belonged to genogroup 6B. A new mutation (E164G) was observed in HA2 of two sequences. Neuraminidase genes in two of 12 isolates from fatal cases on prior oseltamivir treatment harboured the H275Y mutation.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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