Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?-Reference-Cited by-同舟云学术

Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?

Published:2017-11-23 Issue:47 Volume:22 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Hurt Aeron¹²,Komadina Naomi²,Deng Yi-Mo²,Kaye Matthew²,Sullivan Sheena³²,Subbarao Kanta¹²,Barr Ian¹²

Affiliation:

1. Department of Microbiology and Immunology, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia

2. WHO Collaborating Centre for Reference and Research on Influenza, The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia

3. School of Global and Population Health, The University of Melbourne, Victoria, Australia

Abstract

For over a decade virtually all A(H3N2) influenza viruses have been resistant to the adamantane class of antivirals. However, during the 2017 influenza season in Australia, 15/461 (3.3%) adamantane-sensitive A(H3N2) viruses encoding serine at residue 31 of the M2 protein were detected, more than the total number identified globally during the last 6 years. A return to wide circulation of adamantane-sensitive A(H3N2) viruses would revive the option of using these drugs for treatment and prophylaxis.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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