Ongoing haemolytic uraemic syndrome (HUS) outbreak caused by sorbitol-fermenting (SF) Shiga toxin-producing Escherichia coli (STEC) O157, Germany, December 2016 to May 2017-Reference-Cited by-同舟云学术

Ongoing haemolytic uraemic syndrome (HUS) outbreak caused by sorbitol-fermenting (SF) Shiga toxin-producing Escherichia coli (STEC) O157, Germany, December 2016 to May 2017

Published:2017-05-25 Issue:21 Volume:22 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Vygen-Bonnet Sabine¹,Rosner Bettina¹,Wilking Hendrik¹,Fruth Angelika²,Prager Rita²,Kossow Annelene³,Lang Christina²,Simon Sandra²,Seidel Juliane¹⁴⁵,Faber Mirko¹,Schielke Anika¹,Michaelis Kai¹,Holzer Alexandra¹,Kamphausen Rolf⁶,Kalhöfer Daniela⁷,Thole Sebastian⁵⁷,Mellmann Alexander³,Flieger Antje²,Stark Klaus¹

Affiliation:

1. Robert Koch-Institute, Department of Infectious Diseases Epidemiology, Berlin, Germany

2. Robert Koch-Institute, Department of Infectious Diseases, National Reference Centre for Salmonella and other Bacterial Enteric Pathogens, Wernigerode, Germany

3. University Hospital of Münster, Consultant Laboratory for HUS, Münster, Germany

4. Postgraduate Training for Applied Epidemiology, Robert Koch Institute, Berlin, Germany

5. European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden

6. Ministry of Climate Protection, Environment, Agriculture, Nature Conservation and Consumer Protection of the state of North Rhine-Westphalia, Düsseldorf, Germany

7. North Rhine-Westphalia, Centre for Health, Department of Infectiology and Hygiene, Münster, Germany

Abstract

We report an ongoing, protracted and geographically dispersed outbreak of haemolytic uraemic syndrome (HUS) and gastroenteritis in Germany, involving 30 cases since December 2016. The outbreak was caused by the sorbitol-fermenting immotile variant of Shiga toxin-producing (STEC) Escherichia coli O157. Molecular typing revealed close relatedness between isolates from 14 cases. One HUS patient died. Results of a case–control study suggest packaged minced meat as the most likely food vehicle. Food safety investigations are ongoing.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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