Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019-Reference-Cited by-同舟云学术

Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019

Published:2019-08-22 Issue:34 Volume:24 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Hammerum Anette M¹,Justesen Ulrik S²,Pinholt Mette³,Roer Louise¹,Kaya Hülya¹,Worning Peder³,Nygaard Sanne⁴,Kemp Michael²,Clausen Marianne Engell⁵,Nielsen Karen Leth⁶,Samulioniené Jurgita⁷,Kjærsgaard Mona⁸,Østergaard Claus⁹,Coia John¹⁰,Søndergaard Turid Snekloth¹¹,Gaini Shahin¹²¹³¹⁴,Schønning Kristian¹⁵³,Westh Henrik¹⁵³,Hasman Henrik¹,Holzknecht Barbara Juliane⁴

Affiliation:

1. Department for Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark

2. Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark

3. Department of Clinical Microbiology, Hvidovre University Hospital, Hvidovre, Denmark

4. Department of Clinical Microbiology, Herlev and Gentofte University Hospital, Herlev, Denmark

5. Department of Clinical Microbiology, Slagelse Hospital, Slagelse, Denmark

6. Department of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark

7. Department of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark

8. Department of Clinical Microbiology, Aarhus University Hospital, Aarhus, Denmark

9. Department of Clinical Microbiology, Lillebaelt Hospital, Vejle, Denmark

10. Department of Clinical Microbiology, Hospital South West Jutland, Esbjerg, Denmark

11. Department of Clinical Microbiology, Hospital Sønderjylland, Sønderborg, Denmark

12. Centre of Health Research, University of the Faroe Islands, Torshavn, Faroe Islands

13. Department of Infectious Diseases, Odense University Hospital, Odense, Denmark

14. Medical Department, National Hospital Faroe Islands, Torshavn, Faroe Islands

15. Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

Abstract

We describe clonal shifts in vanA Enterococcus faecium isolates from clinical samples obtained from patients in Denmark from 2015 to the first quarter (Q1) of 2019. During Q1 2019, the vancomycin-variable enterococci (VVE) ST1421-CT1134 vanA E. faecium became the most dominant vanA E. faecium clone and has spread to all five regions in Denmark. Among 174 E. faecium isolates with vanA, vanB or vanA/vanB genes in Q1 2019, 44% belonged to this type.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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