Presentation with gastrointestinal symptoms and high case fatality associated with group W meningococcal disease (MenW) in teenagers, England, July 2015 to January 2016

Author:

Campbell Helen1,Parikh Sydel R1,Borrow Ray2,Kaczmarski Ed2,Ramsay Mary E1,Ladhani Shamez N13

Affiliation:

1. Immunisation Department, Public Health England, London United Kingdom

2. Meningococcal Reference Unit, Public Health England, Manchester United Kingdom

3. St. George’s University of London, United Kingdom

Abstract

Atypical clinical presentations associated with group W meningococcal disease (MenW) are well-described and include pneumonia, septic arthritis, endocarditis and epiglottitis/supraglottitis. Following anecdotal reports of teenagers presenting with predominantly gastrointestinal symptoms, we undertook a case review of MenW cases in 15 to 19 year-olds diagnosed in England between July 2015 and January 2016. Of the 15 cases, seven presented with a short history of nausea, vomiting and diarrhoea; five of these seven cases died within 24 hours of presentation to hospital.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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