Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018-Reference-Cited by-同舟云学术

Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018

Published:2018-10-18 Issue:42 Volume:23 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Becker Sören L.¹^ORCID,Berger Fabian K.¹,Feldner Susanne K.²,Karliova Irem²,Haber Manfred³,Mellmann Alexander⁴,Schäfers Hans-Joachim²,Gärtner Barbara¹

Affiliation:

1. Institute of Medical Microbiology and Hygiene, Saarland University, Homburg/Saar, Germany

2. Department of Thoracic and Cardiovascular Surgery, Saarland University, Homburg/Saar, Germany

3. Hospital Pharmacy, Saarland University, Homburg/Saar, Germany

4. Institute of Hygiene, University Hospital Münster, Münster, Germany

Abstract

Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. Two patients died of septic multi-organ failure. Whole-genome sequencing detected genetically identical B. cepacia complex strains in patient samples, from a batch of octenidine mouthwash solution, which had been used for nursing care, as well as in samples obtained from the manufacturer during production. Contamination of medical products during manufacturing may lead to international outbreaks.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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