Usutu virus infections among blood donors, Austria, July and August 2017 – Raising awareness for diagnostic challenges

Author:

Bakonyi Tamás123,Jungbauer Christof41,Aberle Stephan W.51,Kolodziejek Jolanta3,Dimmel Katharina3,Stiasny Karin5,Allerberger Franz6,Nowotny Norbert713

Affiliation:

1. These authors contributed equally to this article and share first authorship

2. Department of Microbiology and Infectious Diseases, University of Veterinary Medicine, Budapest, Hungary

3. Viral Zoonoses, Emerging and Vector-Borne Infections Group, Institute of Virology, University of Veterinary Medicine Vienna, Vienna, Austria

4. Austrian Red Cross, Blood Service for Vienna, Lower Austria and Burgenland, Vienna, Austria

5. Center for Virology, Medical University of Vienna, Vienna, Austria

6. Austrian Agency for Health and Food Safety (AGES), Vienna, Austria

7. Department of Basic Medical Sciences, College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates

Abstract

Between July and August 2017, seven of 12,047 blood donations from eastern Austria, reacted positive to West Nile virus (WNV) in the cobas test (Roche). Follow-up investigations revealed Usutu virus (USUV) nucleic acid in six of these. Retrospective analyses of four blood donors diagnosed as WNV-infected in 2016 showed one USUV positive. Blood transfusion services and public health authorities in USUV-endemic areas should be aware of a possible increase of human USUV infections.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference26 articles.

1. West Nile virus positive blood donation and subsequent entomological investigation, Austria, 2014.;Kolodziejek;PLoS One,2015

2. Emergence of Usutu virus, an African mosquito-borne flavivirus of the Japanese encephalitis virus group, central Europe.;Weissenböck;Emerg Infect Dis,2002

3. Usutu virus, Italy, 1996.;Weissenböck;Emerg Infect Dis,2013

4. The complete sequence of a West Nile virus lineage 2 strain detected in a Hyalomma marginatum marginatum tick collected from a song thrush (Turdus philomelos) in eastern Romania in 2013 revealed closest genetic relationship to strain Volgograd 2007.;Kolodziejek;PLoS One,2014

5. Complete genome analysis and molecular characterization of Usutu virus that emerged in Austria in 2001: comparison with the South African strain SAAR-1776 and other flaviviruses.;Bakonyi;Virology,2004

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