Genetic characterisation of novel, highly pathogenic avian influenza (HPAI) H5N6 viruses isolated in birds, South Korea, November 2016

Author:

Si Young-Jae12,Lee In Won12,Kim Eun-Ha1,Kim Young-Il1,Kwon Hyeok-Il1,Park Su-Jin1,Nguyen Hiep Dinh1,Kim Se Mi1,Kwon Jin-Jung1,Choi Won-Suk1,Beak Yun Hee1,Song Min-Suk1,Kim Chul-Joong3,Webby Richard J.4,Choi Young-Ki1

Affiliation:

1. College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea

2. These authors contributed equally to this work

3. College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea

4. Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States

Abstract

A novel genotype of H5N6 influenza viruses was isolated from migratory birds in South Korea during November 2016. Domestic outbreaks of this virus were associated with die-offs of wild birds near reported poultry cases in Chungbuk province, central South Korea. Genetic analysis and animal studies demonstrated that the Korean H5N6 viruses are highly pathogenic avian influenza (HPAI) viruses and that these viruses are novel reassortants of at least three different subtypes (H5N6, H4N2 and H1N1).

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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