Very low risk of monkeypox among staff and students after exposure to a confirmed case in educational settings, England, May to July 2022

Author:

Ladhani Shamez N12,Aiano Felicity2,Edwards David S3,Perkins Samantha4,Khan Wazirzada M4,Iyanger Nalini5,Whittaker Elizabeth6,Cohen Jonathan M7,Ho David7,Hopkins Susan8,Ramsay Mary E2,Chow J Yimmy5

Affiliation:

1. Paediatric Infectious Diseases Research Group, St. George’s University of London, London, United Kingdom

2. Immunisation Division, UK Health Security Agency, London, United Kingdom

3. UK Health Security Agency East of England Health Protection Team, Mildenhall, United Kingdom

4. UK Health Security Agency, South London Health Protection Team and the London Coordination and Response Cell, London, United Kingdom

5. UK Health Security Agency Northwest London Health Protection Team and the London Coordination and Response Cell, London, United Kingdom

6. Paediatric Infectious Diseases Department, Imperial College London, London, United Kingdom

7. Paediatric Immunology and Infectious Diseases, Evelina London Children's Hospital, London, United Kingdom

8. Clinical and Public Health Group, UK Health Security Agency, London, United Kingdom

Abstract

We investigated a secondary school (11–16 year-olds), a primary school (5–11 year-olds), reception year (4–5 year-olds) and a nursery (2–5 year-olds) following confirmed monkeypox in an adult in each educational setting during June and July 2022. MVA-BN vaccine was offered up to 14 days post exposure to 186 children < 12 years and 21 were vaccinated. No secondary cases occurred among at least 340 exposed students and more than 100 exposed staff during the 28-day follow-up period.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference14 articles.

1. Global Health. Monkeypox 2022 global epidemiology; report 2022-09-23. Global Health; 2022. Available from: https://www.monkeypox.global.health

2. European Centre for Disease Prevention and Control (ECDC). Monkeypox situation update, as of 13 September 2022. Stockholm: ECDC; 2022. Available from: https://www.ecdc.europa.eu/en/news-events/monkeypox-situation-update#:~:text=Since%20the%20start%20of%20the%20monkeypox%20outbreak%20and,%285%29%2C%20Lithuania%20%285%29%2C%20Bulgaria%20%284%29%20and%20Latvia%20%284%29

3. Monkeypox virus infections in children in Spain during the first months of the 2022 outbreak.;Aguilera-Alonso;Lancet Child Adolesc Health,2022

4. Centers for Disease Control and Prevention (CDC). Monkeypox cases by age and gender, race/ethnicity, and symptoms. Atlanta: CDC. [Accessed: 22 Sep 2022]. Available from: https://www.cdc.gov/poxvirus/monkeypox/response/2022/demographics.html

5. Sigodo M, Weston K. School sends children home over fear of outbreak following confirmed monkeypox case. Mirror Online; 2022. https://www.mirror.co.uk/news/uk-news/school-sends-children-home-over-27487452

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