Sustained increase of paediatric invasive Streptococcus pyogenes infections dominated by M1UK and diverse emm12 isolates, Portugal, September 2022 to May 2023-Reference-Cited by-同舟云学术

Sustained increase of paediatric invasive Streptococcus pyogenes infections dominated by M1UK and diverse emm12 isolates, Portugal, September 2022 to May 2023

Published:2023-09-07 Issue:36 Volume:28 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Gouveia Catarina¹^ORCID,Bajanca-Lavado Maria Paula²^ORCID,Mamede Rafael³^ORCID,Araújo Carvalho Ana¹^ORCID,Rodrigues Fernanda⁴^ORCID,Melo-Cristino José³,Ramirez Mario³^ORCID,Friães Ana³^ORCID, ,

Affiliation:

1. Infectious Diseases Unit, Pediatric Department, Hospital de Dona Estefânia, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal

2. Laboratório Nacional de Referência a Infeções Respiratórias a Agentes Bacterianos, Departamento de Doenças Infeciosas, Instituto Nacional de Saúde Dr. Ricardo Jorge, Lisbon, Portugal

3. Instituto de Microbiologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal

4. Hospital Pediátrico, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal

Abstract

Since autumn 2022, observed numbers of paediatric invasive group A Streptococcus infections in Portugal (n = 89) were higher than in pre-COVID-19 seasons. Between September 2022 and May 2023, the dominant diagnoses were pneumonia (25/79), mostly with empyema (20/25), and sepsis (22/79). A number of cases required admission to intensive care (27/79) and surgery (35/79), and the case fatality rate was 5.1% (4/79). Genomic sequencing (n = 55) revealed multiple genetic lineages, dominated by the M1UK sublineage (26/55) and more diverse emm12 isolates (12/55).

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference20 articles.

1. European Centre for Disease Prevention and Control (ECDC). Increase in invasive group A streptococcal infections among children in Europe, including fatalities. Stockholm: ECDC; 2022. Available from: https://www.ecdc.europa.eu/en/news-events/increase-invasive-group-streptococcal-infections-among-children-europe-including

2. Standardization of epidemiological surveillance of invasive group A streptococcal infections.;Miller;Open Forum Infect Dis,2022

3. Annotated whole-genome multilocus sequence typing schema for scalable high-resolution typing of Streptococcus pyogenes.;Friães;J Clin Microbiol,2022

4. Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study.;Lynskey;Lancet Infect Dis,2019

5. Increase in invasive group A streptococcal infections and emergence of novel, rapidly expanding sub-lineage of the virulent Streptococcus pyogenes M1 clone, Denmark, 2023.;Johannesen;Euro Surveill,2023

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Complicated pneumonia caused by group A Streptococcus in children - 2022/2023 infectious season outbreak and update on clinical characteristics;Journal of Infection and Chemotherapy;2024-10

2. Chains of misery: surging invasive group A streptococcal disease;Current Opinion in Infectious Diseases;2024-09-09

3. Infections invasives à Streptocoque du groupe A chez l’enfant;Journal de Pédiatrie et de Puériculture;2024-09

4. Nationwide upsurge in invasive disease in the context of longitudinal surveillance of carriage and invasive Streptococcus pyogenes 2009–2023, the Netherlands: a molecular epidemiological study;Journal of Clinical Microbiology;2024-08-28

5. Divergent effects of emm types 1 and 12 on invasive group A streptococcal infections—results of a retrospective cohort study, Germany 2023;Journal of Clinical Microbiology;2024-08-14