Estimation of COVID-19 vaccine effectiveness against hospitalisation in individuals aged ≥ 65 years using electronic health registries; a pilot study in four EU/EEA countries, October 2021 to March 2022-Reference-Cited by-同舟云学术

Estimation of COVID-19 vaccine effectiveness against hospitalisation in individuals aged ≥ 65 years using electronic health registries; a pilot study in four EU/EEA countries, October 2021 to March 2022

Published:2022-07-28 Issue:30 Volume:27 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Sentís Alexis¹^ORCID,Kislaya Irina²,Nicolay Nathalie³,Meijerink Hinta⁴,Starrfelt Jostein⁴,Martínez-Baz Iván⁵⁶,Castilla Jesús⁵⁶,Nielsen Katrine Finderup⁷,Hansen Christian Holm⁷,Emborg Hanne-Dorthe⁷,Nardone Anthony¹,Derrough Tarik³,Valenciano Marta¹,Nunes Baltazar²,Monge Susana⁸⁹,

Affiliation:

1. Epidemiology Department, Epiconcept, Paris, France

2. Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA), Lisbon, Portugal

3. Vaccine preventable diseases and Immunisation, European Centre for Disease Prevention and Control (ECDC), Solna, Sweden

4. Norwegian Institute of Public Health (NIPH), Oslo, Norway

5. CIBER on Epidemiology and Public Health (CIBERESP), Madrid, Spain

6. Instituto de Salud Pública de Navarra - IdiSNA, Pamplona, Spain

7. Statens Serum Institut (SSI), Copenhagen, Denmark

8. CIBER on Infectious Diseases (CIBERINFEC), Madrid, Spain

9. Instituto de Salud Carlos III (ISCIII), Madrid, Spain

Abstract

By employing a common protocol and data from electronic health registries in Denmark, Navarre (Spain), Norway and Portugal, we estimated vaccine effectiveness (VE) against hospitalisation due to COVID-19 in individuals aged ≥ 65 years old, without previous documented infection, between October 2021 and March 2022. VE was higher in 65–79-year-olds compared with ≥ 80-year-olds and in those who received a booster compared with those who were primary vaccinated. VE remained high (ca 80%) between ≥ 12 and < 24 weeks after the first booster administration, and after Omicron became dominant.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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