Increasing risk of breakthrough COVID-19 in outbreaks with high attack rates in European long-term care facilities, July to October 2021

Author:

Suetens Carl1,Kinross Pete1,Gallego Berciano Pilar2,Arroyo Nebreda Virginia2,Hassan Eline3,Calba Clémentine4,Fernandes Eugenia5,Peralta-Santos Andre5,Casaca Pedro5,Shodu Nathalie6,Dequeker Sara6,Kontopidou Flora7,Pappa Lamprini7,Kacelnik Oliver8,Børseth Anita Wang8,O’Connor Lois9,Garvey Patricia9,Liausedienė Rasa10,Valintelienė Rolanda11,Ernst Corinna12,Mossong Joël12,Štefkovičová Mária1314,Prostináková Zuzana14,Danielsen Ann Caroline1,Mougkou Aikaterini1,Lamb Favelle1,Cenciarelli Orlando1,Monnet Dominique L.1,Plachouras Diamantis1

Affiliation:

1. European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden

2. Institute of Health Carlos III, Madrid, Spain

3. Santé publique France, Saint-Maurice, France

4. Santé publique France, Regional Unit Provence-Alps-French Riviera and Corsica, Marseille, France

5. Directorate-General of Health, Lisbon, Portugal

6. Sciensano, Brussels, Belgium

7. Directorate of Epidemiological Surveillance and Intervention for Infectious Diseases NPHO, Athens, Greece

8. Norwegian Institute of Public Health, Oslo, Norway

9. Health Protection Surveillance Centre, Dublin, Ireland

10. National Public Health Centre under The Ministry of Health, Vilnius, Lithuania

11. Public Health Technology Center Institute of Hygiene, Vilnius, Lithuania

12. Health Directorate, Luxembourg, Luxembourg

13. Alexander Dubcek University, Trenčin, Slovakia

14. Regional Public Health Authority, Trenčin, Slovakia

Abstract

We collected data from 10 EU/EEA countries on 240 COVID-19 outbreaks occurring from July−October 2021 in long-term care facilities with high vaccination coverage. Among 17,268 residents, 3,832 (22.2%) COVID-19 cases were reported. Median attack rate was 18.9% (country range: 2.8–52.4%), 17.4% of cases were hospitalised, 10.2% died. In fully vaccinated residents, adjusted relative risk for COVID-19 increased with outbreak attack rate. Findings highlight the importance of early outbreak detection and rapid containment through effective infection prevention and control measures.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference10 articles.

1. European Centre for Disease Prevention and Control (ECDC). Rapid Risk Assessment: COVID-19 outbreaks in long-term care facilities in the EU/EEA in the context of current vaccination coverage. Stockholm: ECDC; 26 Jul 2021. Available from: https://www.ecdc.europa.eu/en/publications-data/rapid-risk-assessment-covid-19-outbreaks-long-term-care-facilities-eueea

2. European Centre for Disease prevention and Control (ECDC). Data collection on COVID-19 outbreaks in closed settings with a completed vaccination programme: long-term care facilities, version 2.0. Stockholm: ECDC;3 Sep 2021. Available from: https://www.ecdc.europa.eu/en/publications-data/data-collection-covid-19-outbreaks-closed-settings-completed-vaccination

3. European Centre for Disease Prevention and Control (ECDC). Case definition for coronavirus disease 2019 (COVID-19), as of 3 December 2020. Stockholm: ECDC; 3 Dec 2020. Available from: https://www.ecdc.europa.eu/en/covid-19/surveillance/case-definition

4. Effectiveness of Pfizer-BioNTech and Moderna Vaccines in Preventing SARS-CoV-2 Infection Among Nursing Home Residents Before and During Widespread Circulation of the SARS-CoV-2 B.1.617.2 (Delta) Variant - National Healthcare Safety Network, March 1-August 1, 2021.;Nanduri;MMWR Morb Mortal Wkly Rep,2021

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