Monkeypox infection presenting as genital rash, Australia, May 2022

Author:

Hammerschlag Yael1,MacLeod Gina1,Papadakis Georgina2,Adan Sanchez Asiel3,Druce Julian2,Taiaroa George4,Savic Ivana2,Mumford Jamie2,Roberts Jason2,Caly Leon42,Friedman Deborah5,Williamson Deborah A42,Cheng Allen C1,McMahon James H61ORCID

Affiliation:

1. Department of Infectious Diseases, Alfred Hospital and Monash University, Melbourne, Australia

2. Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia

3. Northside Clinic, North Fitzroy, Australia

4. Department of Infectious Diseases, University of Melbourne, Melbourne, Australia

5. Public Health Division, Victorian Government Department of Health, Melbourne, Australia

6. Department of Infectious Diseases, Monash Medical Centre, Melbourne, Australia

Abstract

Rapid diagnosis and whole genome sequencing confirmed a case of monkeypox in an HIV-positive individual receiving antiretroviral therapy. The patient had a normal CD4+ T-cell count and suppressed HIV viral load and presented with a genital rash in Melbourne, Australia after return from Europe in May 2022. He subsequently developed systemic illness and disseminated rash and 11 days after symptom onset, he was hospitalised to manage painful bacterial cellulitis of the genital area.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference7 articles.

1. World Health Organization (WHO). Multi-country monkeypox outbreak in non-endemic countries: Update. Geneva: WHO. [Accessed: 31 May 2022]. Available from: https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON388

2. Meyer H, Ropp SL, Esposito JJ. Poxviruses. Diagnostic Virology Protocols. Methods in Molecular Medicine. In: Stephenson J.R., Warnes A, eds.: Springer; 1998.

3. Human monkeypox: clinical features of 282 patients.;Jezek;J Infect Dis,1987

4. Adler H, Gould S, Hine P, Snell LB, Wong W, Houlihan CF, et al. Clinical features and management of human monkeypox: a retrospective observational study in the UK. Lancet Infect Dis. 2022;S1473-3099(22)00228-6.

5. Clinical characteristics of human monkeypox, and risk factors for severe disease.;Huhn;Clin Infect Dis,2005

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