Impact of the Omicron variant on SARS-CoV-2 reinfections in France, March 2021 to February 2022

Author:

Bastard Jonathan1ORCID,Taisne Benjamin1,Figoni Julie1,Mailles Alexandra1ORCID,Durand Julien1,Fayad Myriam1,Josset Laurence23,Maisa Anna1ORCID,van der Werf Sylvie45,Parent du Châtelet Isabelle1,Bernard-Stoecklin Sibylle1

Affiliation:

1. Santé publique France, French national public health agency, Saint-Maurice, France

2. CIRI, Centre International de Recherche en Infectiologie, Team VirPath, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France

3. Laboratoire de Virologie, Institut des Agents Infectieux, Laboratoire associé au Centre National de Référence des virus des infections respiratoires, Hospices Civils de Lyon, Lyon, France

4. National Reference Center for Respiratory Viruses, Institut Pasteur, Paris, France

5. Molecular Genetics of RNA Viruses, Department of Virology, Institut Pasteur, CNRS UMR 3569, Université Paris Cité, Paris, France

Abstract

Since the first reports in summer 2020, SARS-CoV-2 reinfections have raised concerns about the immunogenicity of the virus, which will affect SARS-CoV-2 epidemiology and possibly the burden of COVID-19 on our societies in the future. This study provides data on the frequency and characteristics of possible reinfections, using the French national COVID-19 testing database. The Omicron variant had a large impact on the frequency of possible reinfections in France, which represented 3.8% of all confirmed COVID-19 cases since December 2021.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference19 articles.

1. Protection against the Omicron variant from previous SARS-CoV-2 infection.;Altarawneh;N Engl J Med,2022

2. Increased risk of infection with SARS-CoV-2 Omicron BA.1 compared with Delta in vaccinated and previously infected individuals, the Netherlands, 22 November 2021 to 19 January 2022.;Eggink;Euro Surveill,2022

3. Breakthrough infections with SARS-CoV-2 omicron despite mRNA vaccine booster dose.;Kuhlmann;Lancet,2022

4. World Health Organization (WHO). Weekly epidemiological update on COVID-19 - 22 February 2022. Edition 80. Geneva: WHO; 2022. Available from: https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19---22-february-2022

5. Considerable escape of SARS-CoV-2 Omicron to antibody neutralization.;Planas;Nature,2022

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