Ongoing mpox outbreak in Kamituga, South Kivu province, associated with monkeypox virus of a novel Clade I sub-lineage, Democratic Republic of the Congo, 2024-Reference-Cited by-同舟云学术

Ongoing mpox outbreak in Kamituga, South Kivu province, associated with monkeypox virus of a novel Clade I sub-lineage, Democratic Republic of the Congo, 2024

Published:2024-03-14 Issue:11 Volume:29 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Masirika Leandre Murhula¹²,Udahemuka Jean Claude³⁴,Schuele Leonard⁵,Ndishimye Pacifique⁶⁷³,Otani Saria⁸,Mbiribindi Justin Bengehya⁹,Marekani Jean M.¹⁰,Mambo Léandre Mutimbwa¹¹,Bubala Nadine Malyamungu¹²,Boter Marjan⁵,Nieuwenhuijse David F.⁵,Lang Trudie¹³,Kalalizi Ernest Balyahamwabo¹,Musabyimana Jean Pierre³¹⁴,Aarestrup Frank M.⁸,Koopmans Marion⁵,Oude Munnink Bas B.¹⁵⁵,Siangoli Freddy Belesi¹⁵⁹

Affiliation:

1. SaBio Instituto de Investigación en Recursos Cinegéticos IREC (Universidad de Castilla-La Mancha & CSIC), Ciudad Real, Spain

2. Centre de Recherche en Sciences Naturelles de Lwiro, DS Bukavu, South Kivu, Bukavu, Democratic Republic of the Congo

3. Stansile Research Organization, Kigali, Rwanda

4. Department of Veterinary Medicine, University of Rwanda, Nyagatare, Rwanda

5. Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands

6. Research and Innovation Centre, African Institute for Mathematical Sciences, Kigali, Rwanda

7. Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada

8. Research Group for Genomic Epidemiology, National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark

9. Division Provinciale de la Santé, South Kivu, Bukavu, Democratic Republic of the Congo

10. Unit of Animal Production and Health, Nature Conservation and Development, Department of Biology, Faculty of Science, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

11. Zone de Santé de Kamituga, Kamituga, South Kivu, Bukavu, Democratic Republic of the Congo

12. Hôpital Général de Référence de Kamituga, South Kivu, Bukavu, Democratic Republic of the Congo

13. The Global Health Network, Oxford University, Oxford, United Kingdom

14. Research, innovation and data science division, Rwanda Biomedical Center, Kigali, Rwanda

15. These authors contributed equally

Abstract

Since the beginning of 2023, the number of people with suspected monkeypox virus (MPXV) infection have sharply increased in the Democratic Republic of the Congo (DRC). We report near-to-complete MPXV genome sequences derived from six cases from the South Kivu province. Phylogenetic analyses reveal that the MPXV affecting the cases belongs to a novel Clade I sub-lineage. The outbreak strain genome lacks the target sequence of the probe and primers of a commonly used Clade I-specific real-time PCR.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Reference20 articles.

1. World Health Organization (WHO). Mpox (monkeypox) - Democratic Republic of the Congo. Geneva: WHO; 23 Nov 2023. Available from: https://www.who.int/emergencies/disease-outbreak-news/item/2023-DON493

2. Multi-country outbreak of mpox. External situation report#30 – 25 November 2023. Geneva: World Health Organization. [Accessed 14 Feb 2024]. Available from: https://www.who.int/publications/m/item/multi-country-outbreak-of-mpox--external-situation-report-30---25-november-2023

3. Clade I-Associated Mpox Cases Associated with Sexual Contact, the Democratic Republic of the Congo.;Kibungu;Emerg Infect Dis,2024

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