Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021-Reference-Cited by-同舟云学术

Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021

Published:2021-04-22 Issue:16 Volume:26 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Jungnick Sabrina¹²,Hobmaier Bernhard¹²,Mautner Lena³,Hoyos Mona³,Haase Maren³,Baiker Armin³,Lahne Heidi²,Eberle Ute²,Wimmer Clara²,Hepner Sabrina²,Sprenger Annika²,Berger Carola²,Dangel Alexandra²,Wildner Manfred⁴⁵,Liebl Bernhard⁴⁵,Ackermann Nikolaus²,Sing Andreas⁵²,Fingerle Volker²,

Affiliation:

1. These authors contributed equally to this work

2. Public Health Microbiology Unit, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany

3. Unit of molecular biologic analytics and biogenetics, Bavarian Health and Food Safety Authority, Oberschleißheim, Germany

4. Bavarian State Institute of Health, Oberschleißheim, Germany

5. Ludwig Maximilians-Universität, Munich, Germany

Abstract

SARS-CoV-2 variants of concern (VOC) should not escape molecular surveillance. We investigated if SARS-CoV-2 rapid antigen tests (RATs) could detect B.1.1.7 and B.1.351 VOCs in certain laboratory conditions. Infectious cell culture supernatants containing B.1.1.7, B.1.351 or non-VOC SARS-CoV-2 were respectively diluted both in DMEM and saliva. Dilutions were analysed with Roche, Siemens, Abbott, nal von minden and RapiGEN RATs. While further studies with appropriate real-life clinical samples are warranted, all RATs detected B.1.1.7 and B.1.351, generally comparable to non-VOC strain.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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