Autochthonous West Nile virus infection outbreak in humans, Leipzig, Germany, August to September 2020

Author:

Pietsch Corinna1ORCID,Michalski Dominik2ORCID,Münch Johannes3,Petros Sirak4ORCID,Bergs Sandra1,Trawinski Henning5ORCID,Lübbert Christoph5ORCID,Liebert Uwe G1

Affiliation:

1. Institute of Virology, Leipzig University Hospital, Leipzig, Germany; Interdisciplinary Centre for Infectious Diseases, Leipzig University Hospital, Leipzig, Germany

2. Department of Neurology, Leipzig University Hospital, Leipzig, Germany

3. Division of Nephrology, Department of Endocrinology, Nephrology and Rheumatology, Leipzig University Hospital, Leipzig, Germany

4. Medical ICU, Leipzig University Hospital, Leipzig, Germany

5. Division of Infectious Diseases and Tropical Medicine, Department of Medicine II, Leipzig University Hospital, Leipzig, Germany; Interdisciplinary Centre for Infectious Diseases, Leipzig University Hospital, Leipzig, Germany

Abstract

Following a distinct summer heat wave, nine autochthonous cases of West Nile fever and West Nile neuroinvasive disease, including one fatality, were observed in Leipzig, Germany, in August and September 2020. Phylogenetic analysis demonstrated close relationships in viruses from humans, animals and mosquitos in eastern Germany, obtained during the preceding 2 years. The described large cluster of autochthonous West Nile virus infections in Germany indicates endemic seasonal circulation of lineage 2 viruses in the area.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference21 articles.

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3. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods.;Tamura;Mol Biol Evol,2011

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