Epidemiological characterisation of the first 785 SARS-CoV-2 Omicron variant cases in Denmark, December 2021

Author:

Espenhain Laura1ORCID,Funk Tjede21ORCID,Overvad Maria1ORCID,Edslev Sofie Marie3ORCID,Fonager Jannik4ORCID,Ingham Anna Cäcilia3ORCID,Rasmussen Morten4,Madsen Sarah Leth5,Espersen Caroline Hjorth1,Sieber Raphael N.3ORCID,Stegger Marc3ORCID,Gunalan Vithiagaran4ORCID,Wilkowski Bartlomiej67,Larsen Nicolai Balle7ORCID,Legarth Rebecca1,Cohen Arieh Sierra7ORCID,Nielsen Finn8,Lam Janni Uyen Hoa8,Lavik Kjetil Erdogan8,Karakis Marianne8,Spiess Katja4ORCID,Marving Ellinor4ORCID,Nielsen Christian67,Wiid Svarrer Christina3ORCID,Bybjerg-Grauholm Jonas9ORCID,Olsen Stefan Schytte8,Jensen Anders67,Krause Tyra Grove10,Müller Luise1

Affiliation:

1. Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark

2. European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control, (ECDC), Stockholm, Sweden

3. Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark

4. Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark

5. COVID-19 tracing Unit, Danish Patient Safety Authority, Copenhagen, Denmark

6. Danish National Biobank, Statens Serum Institut, Copenhagen, Denmark

7. TestCenter Denmark, Statens Serum Institut, Copenhagen, Denmark

8. The Data integration and Analysis Secretariat, Statens Serum Institut, Copenhagen, Denmark

9. Congenital disorders, Statens Serum Institut, Copenhagen, Denmark

10. Epidemiological Infectious Disease Preparedness, Statens Serum Institut, Copenhagen, Denmark

Abstract

By 9 December 2021, 785 SARS-CoV-2 Omicron variant cases have been identified in Denmark. Most cases were fully (76%) or booster-vaccinated (7.1%); 34 (4.3%) had a previous SARS-CoV-2 infection. The majority of cases with available information reported symptoms (509/666; 76%) and most were infected in Denmark (588/644; 91%). One in five cases cannot be linked to previous cases, indicating widespread community transmission. Nine cases have been hospitalised, one required intensive care and no deaths have been registered.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference19 articles.

1. World Health Organization (WHO). Classification of Omicron (B.1.1.529): SARS-CoV-2 variant of concern. Geneva: WHO; 2021. Available from: https://www.who.int/news/item/26-11-2021-classification-of-omicron-(b.1.1.529)-sars-cov-2-variant-of-concern

2. Statens Serum Institut (SSI). Covid-19 – Danmark (kommunalt). [COVID-19 Denmark (by municipality)]. Copenhagen: SSI. [Accessed: 9 Dec 2021]. Danish. Available from: https://experience.arcgis.com/experience/aa41b29149f24e20a4007a0c4e13db1d/page/page_0

3. Statens Serum Institut (SSI). Covid-19 – Danmark (regionalt). [COVID-19 Denmark (by region)]. Copenhagen: SSI. [Accessed: 9 Dec 2021]. Danish. Available from: https://experience.arcgis.com/experience/aa41b29149f24e20a4007a0c4e13db1d/page/page_3

4. Danish Covid-19 Genome Consortium. Genomic overview of SARS-CoV-2 in Denmark. Copenhagen: Statens Serum Institut. [Accessed: 14 December 2021]. Available from: https://www.covid19genomics.dk/statistics

5. Spiess K, Gunalan V, Marving E, Nielsen SH, Jørgensen MGP, Fomsgaard AS, et al. Rapid surveillance platforms for key SARS-CoV-2 mutations in Denmark. medRxiv. 2021:2021.10.25.21265484. Preprint. https://doi.org/10.1101/2021.10.25.21265484

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