COVID-19 mRNA vaccine effectiveness (second and first booster dose) against hospitalisation and death during Omicron BA.5 circulation: cohort study based on electronic health records, Portugal, May to July 2022

Author:

Kislaya Irina12ORCID,Machado Ausenda12,Magalhães Sarah3,Rodrigues Ana Paula2,Franco Rafael3,Leite Pedro Pinto4,Dias Carlos Matias12,Nunes Baltazar12

Affiliation:

1. Centro de Investigação em Saúde Pública, Escola Nacional de Saúde Pública, Universidade NOVA de Lisboa, Lisbon, Portugal

2. Departamento de Epidemiologia, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisbon, Portugal

3. Serviços Partilhados do Ministério da Saúde, Lisbon, Portugal

4. Direção de Serviços de Informação e Análise, Direção-Geral da Saúde, Lisbon, Portugal

Abstract

We measured vaccine effectiveness (VE) against COVID-19-related severe outcomes in elderly people in Portugal between May and July 2022. In ≥ 80 year-olds, the second booster dose VE was 81% (95% CI: 75–85) and 82% (95% CI: 77–85), respectively, against COVID-19-related hospitalisation and death. The first booster dose VE was 63% (95% CI: 55–70) in ≥ 80 year-olds and 74% (95% CI: 66–80) in 60–79 year-olds against hospitalisation, and 63% (95% CI: 57–69) and 65% (95% CI: 54–74) against death.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference11 articles.

1. Direção-Geral da Saúde. Norma 02/2021 - Campanha de Vacinação Contra a COVID-19 - Dose de Reforço. [Standard 02/2021 - Vaccination campaign against COVID-19 – Booster dose]. Lisbon: Direção-Geral da Saúde; 2021. Portuguese. Available from: https://www.dgs.pt/normas-orientacoes-e-informacoes/normas-e-circulares-normativas/norma-n-0022021-de-30012021-pdf.aspx

2. European Centre for Disease Prevention and Control (ECDC), European Medicines Agency (EMA). COVID-19 : Joint statement from ECDC and EMA on the administration of a fourth dose of mRNA vaccines. EMA/204784/2022. Stockholm: ECDC, Amsterdam: EMA; 2022. Available from: https://www.ema.europa.eu/en/documents/public-statement/covid-19-joint-statement-ecdc-ema-administration-fourth-dose-mrna-vaccines_.pdf

3. European Centre for Disease Prevention and Control (ECDC), European Medicines Agency (EMA). COVID-19 : Updated joint statement from ECDC and EMA on the administration of a fourth dose of mRNA vaccines. EMA/635144/2022. Stockholm: ECDC, Amsterdam: EMA;2022. Available from: https://www.ema.europa.eu/en/documents/public-statement/updated-joint-statement-ecdc-ema-additional-booster-doses-covid-19-vaccines_en.pdf

4. mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021.;Nunes;Euro Surveill,2021

5. National Institute of Health (INSA) Doutor Ricardo Jorge. Genetic diversity of the novel coronavirus SARS-CoV-2 (COVID-19) in Portugal. 23 August 2022 report. Lisbon: INSA; 2022. Available from: https://insaflu.insa.pt/covid19/relatorios/PORTUGAL_INSA_SARS_CoV_2_GENETIC_DIVERSITY_situation_report_2022-09-06.pdf

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3