Vaccine breakthrough infection and onward transmission of SARS-CoV-2 Beta (B.1.351) variant, Bavaria, Germany, February to March 2021-Reference-Cited by-同舟云学术

Vaccine breakthrough infection and onward transmission of SARS-CoV-2 Beta (B.1.351) variant, Bavaria, Germany, February to March 2021

Published:2021-07-29 Issue:30 Volume:26 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Kroidl Inge¹²^ORCID,Mecklenburg Ingo³,Schneiderat Peter³,Müller Katharina⁴¹,Girl Philipp⁴¹,Wölfel Roman⁴¹,Sing Andreas⁵,Dangel Alexandra⁵,Wieser Andreas¹²,Hoelscher Michael¹²

Affiliation:

1. German Center for Infection Research (DZIF), Partner Site, Munich, Germany

2. Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Germany

3. Klinikum Landsberg am Lech, Internal Medicine, Landsberg am Lech, Germany

4. Bundeswehr Institute of Microbiology, 80937 Munich, Germany

5. Bavarian Health and Food Safety Authority (LGL), Oberschleissheim, Germany

Abstract

A breakthrough infection occurred in a fully Comirnaty (BNT162b2) vaccinated healthcare worker with high levels of neutralising antibodies with the SARS-CoV-2 B.1.351 (Beta) variant in February 2021. The infection was subsequently transmitted to their unvaccinated spouse. Sequencing revealed an identical virus in both spouses, with a match of all nine single nucleotide polymorphisms typical for B.1.351. To the best of our knowledge, no transmission of any variant of SARS-CoV-2 from a fully vaccinated person has been described before.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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