Effectiveness of COVID-19 vaccines in preventing SARS-CoV-2 infection and hospitalisation, Navarre, Spain, January to April 2021-Reference-Cited by-同舟云学术

Effectiveness of COVID-19 vaccines in preventing SARS-CoV-2 infection and hospitalisation, Navarre, Spain, January to April 2021

Published:2021-05-27 Issue:21 Volume:26 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Martínez-Baz Iván¹²³^ORCID,Miqueleiz Ana⁴¹,Casado Itziar¹²³^ORCID,Navascués Ana⁴¹,Trobajo-Sanmartín Camino⁴¹^ORCID,Burgui Cristina¹²³,Guevara Marcela¹²³^ORCID,Ezpeleta Carmen⁴¹,Castilla Jesús¹²³^ORCID,

Affiliation:

1. Navarra Institute for Health Research (IdiSNA), Pamplona, Spain

2. CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain

3. Instituto de Salud Pública de Navarra, Pamplona, Spain

4. Clinical Microbiology Department, Complejo Hospitalario de Navarra, Pamplona, Spain

Abstract

COVID-19 vaccine effectiveness was evaluated in close contacts of cases diagnosed during January–April 2021. Among 20,961 contacts, 7,240 SARS-CoV-2 infections were confirmed, with 5,467 being symptomatic and 559 leading to hospitalisations. Non-brand-specific one and two dose vaccine effectiveness were respectively, 35% (95% confidence interval (CI): 25 to 44) and 66% (95% CI: 57 to 74) against infections, 42% (95% CI: 31 to 52) and 82% (95% CI: 74 to 88) against symptomatic infection, and 72% (95% CI: 47 to 85) and 95% (95% CI: 62 to 99) against COVID-19 hospitalisation. The second dose significantly increased effectiveness. Findings support continuing complete vaccination.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference20 articles.

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