Nosocomial outbreak caused by the SARS-CoV-2 Delta variant in a highly vaccinated population, Israel, July 2021

Author:

Shitrit Pnina12,Zuckerman Neta S3,Mor Orna43,Gottesman Bat-Sheva51,Chowers Michal51ORCID

Affiliation:

1. Sackler Medical School, Tel-Aviv University, Tel-Aviv Israel

2. Infection Control Unit, Meir Medical Center, Kfar Saba, Israel

3. Central Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Tel-Hashomer, Israel

4. Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel-Aviv University, Israel

5. Infectious Disease Unit, Meir Medical Center, Kfar Saba, Israel

Abstract

A nosocomial outbreak of SARS-CoV-2 Delta variant infected 42 patients, staff and family members; 39 were fully vaccinated. The attack rate was 10.6% (16/151) among exposed staff and reached 23.7% (23/97) among exposed patients in a highly vaccinated population, 16–26 weeks after vaccination (median: 25 weeks). All cases were linked and traced to one patient. Several transmissions occurred between individuals wearing face masks. Fourteen of 23 patients became severely sick or died, raising a question about possible waning immunity.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference14 articles.

1. Ministry of Health. Israel COVID-19 data tracker [Accessed 16 Aug 2021]. Jerusalem: Ministry of Health. Available from: https://www.gov.il/en/departments/guides/information-corona

2. BNT162b2 mRNA Covid-19 vaccine in a nationwide mass vaccination setting.;Dagan;N Engl J Med,2021

3. Nextstrain. All SARS-CoV-2 datasets. [Accessed: 17 Sep 2021]. Available from: https://nextstrain.org/sars-cov-2/#datasets

4. Centers for Disease Control and Prevention (CDC). COVID-19: SARS-CoV-2 variant classifications and definitions. Atlanta: CDC. [Accessed: 15 Aug 2021]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/variants/variant-info.html

5. Ministry of Health. Vaccination guidelines for recovered individuals. Jerusalem: Ministry of Health. [Accessed: 18 Mar 2021]. Hebrew. Available from: https://www.health.gov.il/UnitsOffice/HD/PH/epidemiology/td/286116521.pdf

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