Rapid molecular epidemiology investigations into two recent measles outbreaks in Israel detected from October 2023 to January 2024

Author:

Bucris Efrat12,Indenbaum Victoria12,Levin Tal2,Kanaaneh Yara2,Friedman Keren2,Kushnir Tatyana2,Sheffer Rivka3,Savion Michal3,Salama Matanelle3,Di-castro Noa4,Labay Kozita4,Butera Maya4,Shihada Baraah4,Mor Zohar56,Lustig Yaniv172,Zuckerman Neta S.12

Affiliation:

1. These authors contributed equally to the manuscript

2. Central Virology Laboratory, Public Health Services, Ministry of Health and Sheba Medical Center, Ramat-Gan, Israel

3. Tel Aviv District Health Office, Ministry of Health, Tel Aviv, Israel

4. District Health Office, Ministry of Health, Tiberias, Israel

5. School of Health Sciences, Ashkelon Academic College, Ashkelon, Israel

6. Division of Epidemiology, Ministry of Health, Jerusalem, Israel

7. Faculty of Medicine, Department of Epidemiology and Preventive Medicine, Tel-Aviv University, Tel Aviv, Israel

Abstract

Between late 2023 and early 2024, two measles outbreaks occurred in Israel, each caused by importation of measles virus strains of respective B3 and D8 genotypes. In this study, we validate transmission pathways uncovered by epidemiological investigations using a rapid molecular approach, based on complete measles virus genomes. The presented findings support this rapid molecular approach in complementing conventional contact tracing and highlight its potential for informing public health interventions.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Reference9 articles.

1. A prolonged, nationwide measles outbreak despite very high vaccination coverage in Israel, 2018-19.;Anis;J Infect,2021

2. World Health Organization (WHO). "Eliminating measles and rubella in the WHO European Region" in the description of the outbreaks. p. 15. WHO Regional Office for Europe: Copenhagen. 2024. Available from: https://www.who.int/europe/publications/i/item/9789289060783

3. Mulders MN. “Annex B11.2 Real-time RT-PCR Assays for the Detection of Measles Virus (MeV) N Gene RNA and Human RNase P mRNA (a cellular reference gene) using the ABI 7500 Real-Time Thermocycler”. [Accessed 1 Apr 2024]. Available from: https://www.technet-21.org/en/resources/guidance/annex-b11-2-real-time-rt-pcr-assays-for-the-detection-of-measles-virus-mev-n-gene-rna-and-human-rnase-p-mrna-a-cellular-reference-gene-using-the-abi-7500-real-time-thermocycler

4. Genetic diversity of wild-type measles viruses and the global measles nucleotide surveillance database (MeaNS).;Wkly Epidemiol Rec,2015

5. Assessment of the Utility of Whole Genome Sequencing of Measles Virus in the Characterisation of Outbreaks.;Penedos;PLoS One,2015

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3