Outbreak of Ralstonia pickettii associated with contamination of saline products distributed internationally, the United Kingdom, 2024-Reference-Cited by-同舟云学术

Outbreak of Ralstonia pickettii associated with contamination of saline products distributed internationally, the United Kingdom, 2024

Published:2024-07-04 Issue:27 Volume:29 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Saunders Mike¹²^ORCID,Weaver Amy¹²^ORCID,Stretch Rebecca²^ORCID,Jeyaratnam D²^ORCID,Mirfenderesky Mariyam²^ORCID,Elliott David²^ORCID,Patterson Charlotte²^ORCID,Williams David²^ORCID,Kenna Dervla TD²^ORCID,Turton Jack²,Osman Karen L²^ORCID,Turton Jane F²^ORCID,Brown Colin S²,Elston JWT²^ORCID

Affiliation:

1. These authors contributed equally to this work and share first authorship.

2. United Kingdom Health Security Agency (UKHSA), Colindale, United Kingdom

Abstract

We describe an outbreak of Ralstonia pickettii in the United Kingdom, with isolates genetically indistinguishable from a 2023 Australian outbreak linked to internationally distributed saline solutions. Confirmed cases (n = 3) had bacteraemia, clinically relevant infection, indwelling venous lines and frequent healthcare contact. Multi-stakeholder intervention was required including product recall and risk communications. We recommend a low threshold for investigating clusters of Ralstonia species and similar opportunistic pathogens, considering contaminated product sources. Effective mitigation requires multi-agency partnership and international collaboration.

Publisher

European Centre for Disease Control and Prevention (ECDC)

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