Neonatal Elizabethkingia anophelis meningitis originating from the water reservoir of an automated infant milk dispenser, the Netherlands, February 2024

Author:

Brandsema B Ruben12,Fleurke Ger-Jan3,Rosema Sigrid3,Schins Eke MW4,Helfferich Jelte5,Bathoorn Erik13

Affiliation:

1. These authors contributed equally to this work and share first/last authorship.

2. University Medical Center Groningen, Department of Paediatric Infectious Diseases and Immunity, Groningen, the Netherlands

3. University Medical Center Groningen, Department of Medical Microbiology, Groningen, the Netherlands

4. University Medical Center Groningen, Department of Neonatology, Groningen, the Netherlands

5. University Medical Center Groningen, Department of Neurology, Groningen, the Netherlands

Abstract

Elizabethkingia anophelis is a multidrug-resistant pathogen causing high mortality and morbidity in adults with comorbidities and neonates. We report a Dutch case of E. anophelis meningitis in a neonate, clonally related to samples taken from an automated infant milk dispenser located at the family’s residence. We inform about the emergence of E. anophelis and suggest molecular surveillance in hospitals and other health settings. This is the first case connecting an automated formula dispenser to an invasive infection in a neonate.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Reference13 articles.

1. Elizabethkingia anophelis outbreak in France.;Guerpillon;Infect Dis Now,2022

2. Evolutionary dynamics and genomic features of the Elizabethkingia anophelis 2015 to 2016 Wisconsin outbreak strain.;Perrin;Nat Commun,2017

3. Antimicrobial susceptibility of Elizabethkingia species: report from a reference laboratory.;Comba;J Clin Microbiol,2022

4. European Committee on Antimicrobial Susceptibility Testing (EUCAST). EUCAST guidance on When there are no breakpoints in breakpoint tables? Växjö: EUCAST; 2024. Available from https://www.eucast.org/fileadmin/src/media/PDFs/EUCAST_files/Guidance_documents/When_there_are_no_breakpoints_2024-02-29.pdf

5. Clinical and Laboratory Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing. 34th ed. CLSI supplement M100. Lewis: CLSI; 2024. Available from: https://clsi.org/standards/products/microbiology/documents/m100/

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