PCR testing of traced contacts for SARS-CoV-2 in England, January to July 2021

Author:

Nonnenmacher Toby1,Dandamudi Niharika1,Futschik Matthias Erwin21ORCID,Tunkel Sarah A1ORCID,Kulasegaran-Shylini Raghavendran1ORCID,Germanacos Nick1,Cole-Hamilton Joanna1,Blandford Edward1,Goddard Ashley1,Hillier Joe1,Finer Stephen1,Hopkins Susan1ORCID,Fowler Tom31ORCID

Affiliation:

1. United Kingdom Health Security Agency, London, United Kingdom

2. Faculty of Health, School of Biomedical Sciences, University of Plymouth, Plymouth, United Kingdom

3. William Harvey Research Institute, Queen Mary University of London, London, United Kingdom

Abstract

Background The NHS Test and Trace (NHSTT) programme was established in May 2020 in England to deliver SARS-CoV-2 testing and contact tracing in order to identify infected individuals and reduce COVID-19 spread. To further control transmission, people identified as contacts were asked to self-isolate for 10 days and test only if they became symptomatic. From March 2021, eligibility criteria for PCR testing expanded to include asymptomatic contacts of confirmed cases. Aim To analyse testing patterns of contacts before and after the change in testing guidance in England to assess the impact on PCR testing behaviour with respect to symptom status and contact type. Methods Testing and contact tracing data were extracted from the national data systems and linked. Subsequently, descriptive statistical analysis was applied to identify trends in testing behaviour. Results Between 1 January and 31 July 2021, over 5 million contacts were identified and reached by contact tracers; 42.3% took a PCR test around the time they were traced. Overall positivity rate was 44.3% and consistently higher in symptomatic (60–70%) than asymptomatic (around 20%, March–June) contacts. The proportion of tests taken by asymptomatic contacts increased over time, especially after the change in testing guidance. No link was observed between uptake of PCR tests and vaccination coverage. Fully vaccinated contacts showed lower positivity (23.8%) than those with one dose (37.2%) or unvaccinated (51.0%). Conclusion Almost 1 million asymptomatic contacts were tested for SARS-CoV-2, identifying 214,056 positive cases, demonstrating the value of offering PCR testing to this group.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference35 articles.

1. World Health Organization (WHO). WHO Director-General's opening remarks at the media briefing on COVID-19 - 16 March 2020. Geneva: WHO. [Accessed: 12 Oct 2023]. Available from: https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---16-march-2020

2. Department of Health and Social Care. Government launches NHS Test and Trace service. London: gov.uk; 2020. Available from: https://www.gov.uk/government/news/government-launches-nhs-test-and-trace-service

3. Public Health England and United Kingdom Health Security Agency. Dr Jenny Harries marks official launch of UK Health Security Agency. London: gov.uk; 2021. Available from: https://www.gov.uk/government/news/dr-jenny-harries-marks-official-launch-of-uk-health-security-agency

4. United Kingdom Health Security Agency. UK Health Security Agency (UKHSA): Addressing the impact of health threats on the nation. London: gov.uk; 2021. Available from: https://ukhsa.blog.gov.uk/2021/10/01/uk-health-security-agency-addressing-the-impact-of-health-threats-on-the-nation

5. United Kingdom Health Security Agency (UKHSA). [Withdrawn] Stay at home: guidance for households with possible or confirmed coronavirus (COVID-19) infection (section 6.1.1). London: gov.uk. [Accessed: 2 Oct 2023]. Available from: https://www.gov.uk/government/publications/covid-19-stay-at-home-guidance/stay-at-home-guidance-for-households-with-possible-coronavirus-covid-19-infection#samehousehold

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3