Effectiveness of influenza vaccination in preventing influenza in primary care, Navarre, Spain, 2021/22

Author:

Martínez-Baz Iván123ORCID,Casado Itziar123ORCID,Miqueleiz Ana41,Navascués Ana41,Pozo Francisco52ORCID,Trobajo-Sanmartín Camino123ORCID,Albéniz Esther61,Elía Fernando61,Burgui Cristina123ORCID,Fernández-Huerta Miguel41,Ezpeleta Carmen41,Castilla Jesús123ORCID

Affiliation:

1. Navarre Institute for Health Research (IdiSNA), Pamplona, Spain

2. CIBER Epidemiología y Salud Pública (CIBERESP), Spain

3. Instituto de Salud Pública de Navarra, Pamplona, Spain

4. Clinical Microbiology Department, Hospital Universitario de Navarra, Pamplona, Spain

5. National Centre for Microbiology, Instituto de Salud Carlos III, Madrid, Spain

6. Gerencia de Atención Primaria, Servicio Navarro de Salud-Osasunbidea, Pamplona, Spain

Abstract

Compared with individuals unvaccinated in the current and three previous influenza seasons, in 2021/22, influenza vaccine effectiveness at primary care level was 37% (95% CI: 16 to 52) for current season vaccination, regardless of previous doses, and 35% (95% CI: −3 to 45) for only previous seasons vaccination. Against influenza A(H3N2), estimates were 39% (95% CI: 16 to 55) and 24% (95% CI: −8 to 47) suggesting moderate effectiveness of current season vaccination and possible remaining effect of prior vaccinations.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference12 articles.

1. Sistema de Vigilancia de la Gripe en España. Informe semanal de Vigilancia de la Gripe en España. Semana 20/2022 N° 81. [Weekly report of the influenza surveillance system in Spain 20/2022. N° 81]. Madrid: Instituto de Salud Carlos III. [Accessed: 31 May 2022]. Spanish. Available from: http://vgripe.isciii.es/inicio.do

2. Influenza returns with a season dominated by clade 3C.2a1b.2a.2 A(H3N2) viruses, WHO European Region, 2021/22.;Melidou;Euro Surveill,2022

3. A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22 influenza season up to 25 March 2022.;Emborg;Euro Surveill,2022

4. Interim Estimates of 2021-22 Seasonal Influenza Vaccine Effectiveness - United States, February 2022.;Chung;MMWR Morb Mortal Wkly Rep,2022

5. Use of the vaccination register to evaluate influenza vaccine coverage in seniors in the 2010/11 influenza season, Navarre, Spain.;Aguilar;Euro Surveill,2012

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