Dengue virus serotype 4 and chikungunya virus coinfection in a traveller returning from Luanda, Angola, January 2014

Author:

Parreira R1,Centeno-Lima S2,Lopes A1,Portugal-Calisto D3,Constantino A45,Nina J63

Affiliation:

1. Unidade de Microbiologia Médica (Grupo de Virologia) and Unidade de Parasitologia e Microbiologia Médicas (UPMM), Instituto de Higiene e Medicina Tropical (IHMT), Universidade Nova de Lisboa (UNL), Lisbon, Portugal

2. Unidade de Clínica Tropical and Centro de Malária e Outras Doenças Tropicais (CMDT), Instituto de Higiene e Medicina Tropical (IHMT), Universidade Nova de Lisboa (UNL), Lisbon, Portugal

3. Unidade de Clínica Tropical IHMT/UNL, Lisbon, Portugal

4. St. Maria Hospital–Centro Hospitalar Lisboa Norte, Lisbon, Portugal

5. São Francisco Xavier Hospital–Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal

6. Centro Hospitalar de Lisboa Ocidental/Hospital de Egas Moniz, Lisbon, Portugal

Abstract

A concurrent dengue virus serotype 4 and chikungunya virus infection was detected in a woman in her early 50s returning to Portugal from Luanda, Angola, in January 2014. The clinical, laboratory and molecular findings, involving phylogenetic analyses of partial viral genomic sequences amplified by RT-PCR, are described. Although the circulation of both dengue and chikungunya viruses in Angola has been previously reported, to our knowledge this is the first time coinfection with both viruses has been detected there.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference21 articles.

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2. Lanciotti RS, Calisher CH, Gubler DJ, Chang GJ, Vorndam AV. Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J Clin Microbiol. 1992;30(3):545-51.

3. Pimenta A. Identificação da sequência de encapsidação do genoma do virus Chikungunya (CHIKV). [Identification of the chikungunya vírus (CHIKV) genome packaging sequence] [Master's dissertation]. Lisbon: Instituto de Higiene e Medicina Tropical/Universidade Nova de Lisboa, Portugal; 2013. Portuguese.

4. Strimmer K, von Haeseler A. Nucleotide substitution models. In: Salemi M, Vandamme A-M, editors. The phylogenetic handbook: a practical approach to DNA and protein phylogeny. Cambridge: Cambridge University Press; 2003. p. 72-87.

5. The global distribution and burden of dengue

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