Acute flaccid paralysis following enterovirus D68 associated pneumonia, France, 2014

Author:

Lang M1,Mirand A23,Savy N1,Henquell C32,Maridet S1,Perignon R4,Labbé A1,Peigue-Lafeuille H32

Affiliation:

1. CHU Clermont-Ferrand, NHE, Service de réanimation pédiatrique, Clermont-Ferrand, France

2. CHU Clermont-Ferrand, Laboratoire de Virologie, Centre National de Référence des Enterovirus/Parechovirus – laboratoire associé, Clermont-Ferrand, France

3. Université d’Auvergne, EA4843 Epidémiologie et pathogénie des infections à entérovirus, Clermont-Ferrand, France

4. CHU Clermont-Ferrand, NHE, Département d’imagerie pédiatrique, Clermont-Ferrand, France

Abstract

Human enterovirus D68 (EV-D68) is known to be associated with mild to severe respiratory infections. Recent reports in the United States and Canada of acute flaccid paralysis (AFP) in children with detection of EV-D68 in respiratory samples have raised concerns about the aetiological role of this EV type in severe neurological disease. This case study is the first report of AFP following EV-D68 infection in Europe.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference21 articles.

1. Midgley CM, Jackson MA, Selvarangan R, Turabelidze G, Obringer E, Johnson D, et al. Severe Respiratory Illness Associated with Enterovirus D68 — Missouri and Illinois, 2014. MMWR Morb Mortal Wkly Rep. 2014;63(36):798-9.

2. National Collaborating Centre for Infectious Diseases (NCCID). Disease Debrief: EV-D68. Winnipeg, Manitoba: NCCID. [Accessed 5 Nov 2014]. Available from: http://www.nccid.ca/disease-debrief-ev-d68#Q1

3. Pastula DM, Aliabadi N, Haynes AK, Messacar K, Schreiner T, Maloney J, et al. Acute neurological illness of Unknown etiology in Children – Colorado, August-September 2014. MMWR Morb Mortal Wkly Rep. 2014;63(40):901-2.

4. British Columbia Centre for Disease Control. Emerging Respiratory Virus Bulletin: MERS-CoV, Influenza A(H7N9) and A(H3N2)v, Enterovirus D68. British Columbia: Centre for Disease Control. 4 Oct 2014. Available from: http://www.bccdc.ca/NR/rdonlyres/88FD3DD4-BEB0-4F29-93C0-6093A7AFBD4B/0/Full_ERVUpdate20141004.pdf

5. Enterovirus 68 in Pediatric Patients Hospitalized for Acute Airway Diseases

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