Household transmission of haemolytic uraemic syndrome associated with Escherichia coli O104:H4, south-western France, June 2011

Author:

Aldabe B12,Delmas Y31,Gault G2,Vendrely B3,Llanas B3,Charron M2,Castor C2,Ong N2,Weill F X4,Mariani-Kurkdjian P5,Terrier F6,Desjardin M6,Simões J7,Le Bihan B7,Combe C83,Rolland P82

Affiliation:

1. These authors contributed equally to this work

2. French Institute for Public Health Surveillance (Institut de Veille Sanitaire; InVS), Regional office ‘Cire Aquitaine’, Bordeaux, France

3. Bordeaux University Hospital, Bordeaux, France

4. Institut Pasteur, National Reference Centre for Escherichia coli and Shigella, Paris, France

5. Robert Debré Hospital, Associated Laboratory to the National Reference Centre for Escherichia coli and Shigella, Paris, France

6. Robert Picqué Military Hospital, Villenave-D’Ornon, France

7. Regional Health Agency of Aquitaine, Bordeaux, France

8. Both authors contributed equally to this work

Abstract

Following the outbreak of haemolytic uraemic syndrome (HUS) on June 2011 in south-western France, household transmission due to Escherichia coli O104:H4 was suspected for two cases who developed symptoms 9 and 10 days after onset of symptoms of the index case. The analysis of exposures and of the incubation period is in favour of a secondary transmission within the family. Recommendations should be reinforced to prevent person-to-person transmission within households.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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