HPLC-MS/MS Method for Quantitation of Sildenafil and Its Active Metabolite in Human Plasma-Reference-Cited by-同舟云学术

HPLC-MS/MS Method for Quantitation of Sildenafil and Its Active Metabolite in Human Plasma

Published:2020-09-18 Issue:3 Volume:10 Page:192-200
ISSN:2619-1172
Container-title:The Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products
language:
Short-container-title:Vedomosti Nauchnogo tsentra ekspertizy sredstv meditsinskogo primeneniya

Author:

Rodionov G. G.¹,Shantyr I. I.¹^ORCID,Ushal I. E.¹^ORCID,Svetkina E. V.¹,Kolobova E. A.¹^ORCID,Zakharov K. A.²

Affiliation:

1. Nikiforov Russian Center of Emergency and Radiation Medicine

2. Eco-Safety Research Center, LLC

Publisher

SCEEMP

Reference10 articles.

1. Akhvlediani ND, Matyukhov IP. Current role of sildenafil in the management of erectile dysfunction. Urologiya = Urology. 2018;(2):142–6 (In Russ.) https://doi.org/10.18565/urology.2018.2.142-146

2. Kuznetsov IE, Naumenko EA, Reznichenko NK, Kostyuk AYu, Savyak RP, Oleynikov DS. Development and validation of method for quantitative determination of sildenafil and N-desmethyl sildenafil by HPLC-MS/MS in human blood plasma. ScienceRise: Pharmaceutical Science. 2017;1(5):22–32 (In Russ.) https://doi.org/10.15587/2519-4852.2017.92823

3. Tripathi AS, Sheikh I, Dewani AP, Shelke PG, Bakal RL, Chandewar AV, et al. Development and validation of RP-HPLC method for sildenafil citrate in rat plasma-application to pharmacokinetic studies. Saudi Pharm J. 2013;21(3):317–21. https://doi.org/10.1016/j.jsps.2012.09.003

4. Reddy BPK, Reddy YR. Validation and stability indicating RP-HPLC method for the determination of sildenafil citrate in pharmaceutical formulations and human plasma. J Chem. 2008;5(S2):1117–22. https://doi.org/10.1155/2008/682924

5. Al-Ghazawi M, Tutunji M, AbuRuza S. Simultaneous determination of sildenafil and N-desmethyl sildenafil in human plasma by high-performance liquid chromatography method using electrochemical detection with application to a pharmacokinetic study. J Pharm Biomed Anal. 2007;43(2):613–8. https://doi.org/10.1016/j. jpba.2006.07.028