The relationship between the active cell mass index and complications of liver cirrhosis: ascites and hepatic encephalopathy

Abstract

Changes in body composition, in particular sarcopenia and sarcopenic obesity, are complications of liver cirrhosis affected by unfavorable parent substances. The selection of diet and exercise for at least 8 weeks allows you to get the best results when taken by patients with cirrhosis of the liver. The correlate of motor activity in the bioimpedance analysis of the active fraction of the active cell mass in the lean mass of the human body. Aim of the study. To assess the relationship between increased cell mass and the severity of ascites and hepatic encephalopathy in liver cirrhosis. Material and methods. 46 patients with liver cirrhosis were examined. The component composition of the body is felt with the help of ABC-01 "Medass" devices (STC Medass, Russia). Ascites was assessed during the clinical examination, as well as the results of the examination of the abdominal cavity and retroperitoneal space. Diagnosis of hepatic encephalopathy impact test on the speed of cognitive reaction: "Number connection test". Results. A significant relationship was found between the proportion of active cell mass and the severity of ascites (r = –0.312, p-value = 0.034), indicating that a decrease in active cell mass is a prognostically unfavorable disease for the progression of ascites in patients with liver cirrhosis. Correlation analysis showed the presence of a negative correlation average strength between the values of the share of AKM in TMT and high body weight of PE: r = –0.229 (p value = 0.125), which requires research on studies between the values of the relationship between active cell mass and body weight. hepatic encephalopathy. Conclusion. Sensitive relationships have been found between active cell mass and the severity of liver cirrhosis. Determination of body composition products, in particular the absolute and relative indicators of active cell mass, in patients with liver cirrhosis can be of practical use in compiling promising mathematical models of prognosis.