Author:
OZGOCMEN SALIH,ARDICOGLU OZGE,KAMANLI AYHAN,KAYA ARZU,DURMUS BEKIR,YILDIRIM KADIR,BAYSAL OZLEM,GUR ALI,KARATAY SALIHA,ALTAY ZUHAL,CEVIK REMZI,ERDAL AKIN,ERSOY YUKSEL,SARAC AYSEGUL J.,TEKEOGLU IBRAHIM,UGUR MAHIR,NAS KEMAL,SENEL KAZIM,ULUSOY HASAN
Abstract
Objective.To assess the frequency of juvenile onset ankylosing spondylitis (JOAS) in Turkish patients with AS and to compare with adult onset AS (AOAS) in a cross-sectional study design.Methods.A total of 322 patients were recruited from the joint database of 5 university hospitals in eastern Turkey.Results.Patients with JOAS (n = 43, 13.4%) had significantly longer diagnostic delay (9.21 vs 5.08 yrs), less severe axial involvement and more prevalent uveitis (OR 2.92, 95% CI 1.25–6.79), and peripheral involvement at onset (OR 3.25, 95% CI 1.51–6.98, adjusted for current age; and OR 2.26, 95% CI 1.07–4.76, adjusted for disease duration). Patients with AOAS had higher radiographic scores and more restricted clinimetrics but similar functional limitations and quality of life.Conclusion.JOAS and AOAS had distinctive courses and Turkish patients with AS had similar features compared to other Caucasian patient populations.
Publisher
The Journal of Rheumatology
Subject
Immunology,Immunology and Allergy,Rheumatology
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