Assessing the Reliability of a Semiautomated Segmentation Algorithm for Quantifying Erosions in the Metacarpophalangeal Joints of Patients with Rheumatoid Arthritis

Author:

Tomizza Michael A.,Jessome Matthew A.,Barbosa Joshua,Beattie Karen A.,Bensen William G.,Bobba Raja S.,Cividino Alfred A.,Emond Patrick D.,Gordon Chris,Hart Lawrence,Ioannidis George,Koh Melissa X.P.,Larché Maggie,Tavares Ruben,Tytus Stephen,Adachi Jonathan D.

Abstract

Objective.Assess the reliability of early erosions in rheumatoid arthritis (EERA) software for quantifying erosive damage to the metacarpophalangeal joints of patients with rheumatoid arthritis (RA).Methods.One hundred magnetic resonance image sets from 68 patients with early referral RA were evaluated. Reliability was assessed using 95% limits of agreement and intraclass correlation coefficient (ICC) with 95% CI.Results.Limits of agreement linearly depended on erosion volume: 0.44× between readers and 0.19× within readers. Interrater ICC was 0.976 (95% CI 0.965–0.984) and intrarater ICC was 0.996 (95% CI 0.994–0.997).Conclusion.EERA is highly reproducible for quantifying erosions in patients with early RA.

Publisher

The Journal of Rheumatology

Subject

Immunology,Immunology and Allergy,Rheumatology

Reference17 articles.

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2. Volume measurement of bone erosions in magnetic resonance images of patients with rheumatoid arthritis

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4. OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging Studies. Core set of MRI acquisitions, joint pathology definitions, and the OMERACT RA-MRI scoring system;Østergaard;J Rheumatol,2003

5. OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging Studies. Exercise 3: an international multicenter reliability study using the RA-MRI Score;Lassere;J Rheumatol,2003

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