Diagnostic Arthrocentesis for Suspicion of Gout Is Safe and Well Tolerated

Author:

Taylor William J.,Fransen Jaap,Dalbeth Nicola,Neogi Tuhina,Ralph Schumacher H.,Brown Melanie,Louthrenoo Worawit,Vazquez-Mellado Janitzia,Eliseev Maxim,McCarthy Geraldine,Stamp Lisa K.,Perez-Ruiz Fernando,Sivera Francisca,Ea Hang-Korng,Gerritsen Martijn,Scire Carlo A.,Cavagna Lorenzo,Lin Chingtsai,Chou Yin-Yi,Tausche Anne-Kathrin,da Rocha Castelar-Pinheiro Geraldo,Janssen Matthijs,Chen Jiunn-Horng,Slot Ole,Cimmino Marco,Uhlig Till,Jansen Tim L.

Abstract

Objective.To determine the frequency of adverse events of diagnostic arthrocentesis in patients with possible gout.Methods.Consecutive patients underwent arthrocentesis and were evaluated at 6 weeks to determine adverse events. The 95% CI were obtained by bootstrapping.Results.Arthrocentesis was performed in 910 patients, and 887 (97.5%) were evaluated for adverse events. Any adverse event was observed in 12 participants (1.4%, 95% CI 0.6–2.1). There was 1 case (0.1%, 95% CI 0–0.34) of septic arthritis.Conclusions.Diagnostic arthrocentesis is associated with a low frequency of adverse events. Septic arthritis rarely occurs.

Publisher

The Journal of Rheumatology

Subject

Immunology,Immunology and Allergy,Rheumatology

Reference9 articles.

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5. US Department of Health and Human Services . Common Terminology Criteria for Adverse Events (CTCAE) v4.03; 2010. [Internet. Accessed November 16, 2015.] Available from: http://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03_2010-06-14_QuickReference_5x7.pdf

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