Author:
WEISS PAMELA F.,KLINK ANDREW J.,LUAN XIANQUN,FEUDTNER CHRIS
Abstract
Objective.To determine if hospitalizations for specific infectious exposures are associated with hospital admissions for Henoch-Schönlein purpura (HSP).Methods.We conducted a retrospective cohort study using administrative data of children admitted to 40 children’s hospitals between January 1, 2002, and December 31, 2008. We examined the association of standardized rates of group A ß-hemolytic Streptococcus (GABS), Staphylococcus aureus, parainfluenza, influenza, adenovirus, and respiratory syncytial virus (RSV)-associated hospital admissions with standardized rates of HSP hospital admissions on a month by month basis using autoregressive moving average process models to account for temporal autocorrelation and clustering by hospital.Results.Among the 3,132 admissions for HSP observed over the 7-year study period, hospital admissions were most frequent September through April, but with substantial variability between hospitals for each month. Accounting for these month by month differences within each hospital, the rate of HSP admissions in a given month increased significantly as the standardized rates of GABS (p = 0.01), S. aureus (p < 0.01), and parainfluenza (p = 0.03) admissions increased.Conclusion.Our results demonstrate a local month by month temporal association between hospitalization for GABS, S. aureus, and parainfluenza and hospitalization for HSP. Future investigations will be required to determine causality.
Publisher
The Journal of Rheumatology
Subject
Immunology,Immunology and Allergy,Rheumatology
Reference49 articles.
1. Pediatric rheumatology clinic populations in the United States: results of a 3 year survey. Pediatric Rheumatology Database Research Group;Bowyer;J Rheumatol,1996
2. Sch??nlein-Henoch Purpura in Children and Adults
3. EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides
4. Alterations in the O-linked glycosylation of IgA1 in children with Henoch-Schonlein purpura;Saulsbury;J Rheumatol,1997
5. Abnormal IgA glycosylation in Henoch-Schonlein purpura restricted to patients with clinical nephritis
Cited by
52 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献