Structure elucidation of two differentiation inducing factors (DIF-2 and DIF-3) from the cellular slime mould Dictyostelium discoideum-Reference-Cited by-同舟云学术

Structure elucidation of two differentiation inducing factors (DIF-2 and DIF-3) from the cellular slime mould Dictyostelium discoideum

Published:1988-02-01 Issue:3 Volume:249 Page:903-906
ISSN:0264-6021
Container-title:Biochemical Journal
language:en
Short-container-title:

Author:

Morris H R¹,Masento M S¹,Taylor G W²,Jermyn K A³,Kay R R⁴

Affiliation:

1. Department of Biochemistry, Imperial College of Science and Technology, South Kensington, London SW7 2AZ, U.K.

2. Department of Clinical Pharmacology, Royal Postgraduate Medical School, Hammersmith Hospital, DuCane Road, London W12 OHS, U.K.

3. Imperial Cancer Research Fund, Clare Hall Laboratories, South Mimms, Herts. EN6 3LD, U.K.

4. MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, U.K.

Abstract

Two endogenous differentiation-inducing factors (DIF-2 and DIF-3), which induce stalk-cell differentiation in the cellular slime mould Dictyostelium discoideum, have been identified as the pentan-1-one and monochloro analogues respectively of (1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one). These compounds represent a new chemical class of effector molecules.

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

https://portlandpress.com/biochemj/article-pdf/249/3/903/592476/bj2490903.pdf

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