The Relationship between Plasma Biotin Concentration and Circulating Leucocyte β-Methylcrotonyl-CoA Carboxylase and Propionyl-CoA Carboxylase

Abstract

1. A newly developed biotin assay was used to monitor plasma and urinary biotin concentration after the oral administration of biotin. 2. In two normal subjects, leucocyte propionyl-CoA carboxylase and β-methylcrotonyl-CoA carboxylase were markedly stimulated after the administration of biotin.